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Martine Simonelig Selected Research

Guanabenz (BR 750)

1/2019Pharmacological modulation of the ER stress response ameliorates oculopharyngeal muscular dystrophy.
1/2011Antiprion drugs 6-aminophenanthridine and guanabenz reduce PABPN1 toxicity and aggregation in oculopharyngeal muscular dystrophy.

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Martine Simonelig Research Topics

Disease

5Oculopharyngeal Muscular Dystrophy
01/2022 - 01/2011
2Neoplasms (Cancer)
01/2021 - 01/2013
1Muscular Atrophy (Muscle Atrophy)
01/2022
1Prion Diseases (Transmissible Spongiform Encephalopathies)
01/2021
1Fibrosis (Cirrhosis)
01/2019
1Mitochondrial Diseases (Mitochondrial Disease)
03/2015
1Late Onset Disorders
03/2015
1Neurodegenerative Diseases (Neurodegenerative Disease)
03/2015
1Muscular Diseases (Myopathy)
04/2011
1Alzheimer Disease (Alzheimer's Disease)
05/2009

Drug/Important Bio-Agent (IBA)

3Proteins (Proteins, Gene)FDA Link
01/2021 - 05/2009
3Poly(A)-Binding Protein IIIBA
03/2015 - 05/2009
2Messenger RNA (mRNA)IBA
01/2021 - 03/2015
2Guanabenz (BR 750)FDA Link
01/2019 - 01/2011
2polyalanineIBA
03/2015 - 05/2009
1Proteasome Endopeptidase Complex (Proteasome)IBA
01/2022
1UbiquitinIBA
01/2022
1Piwi-Interacting RNAIBA
01/2021
1Prion ProteinsIBA
01/2021
1Antihypertensive Agents (Antihypertensives)IBA
01/2019
1Pharmaceutical PreparationsIBA
01/2013
1Alanine (L-Alanine)FDA Link
04/2011
16-aminophenanthridineIBA
01/2011